Expresión de búsqueda: PHOSPHODIESTERASE I 
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Descriptor Inglés:   Phosphodiesterase I 
Descriptor Español:   Fosfodiesterasa I 
Descriptor Portugués:   Fosfodiesterase I 
Sinónimos Inglés:   5'-Exonuclease
5'-Nucleotidephosphodiesterase
Alkaline Phosphodiesterase
Alkaline Phosphodiesterase I
Oligonucleate 5'-Nucleotidohydrolase
Orthophosphoric Diester Phosphohydrolase
5' Exonuclease
5' Nucleotidephosphodiesterase
Diester Phosphohydrolase, Orthophosphoric
Oligonucleate 5' Nucleotidohydrolase
Phosphodiesterase I, Alkaline
Phosphodiesterase, Alkaline
Phosphohydrolase, Orthophosphoric Diester  
Categoría:   D08.811.277.352.640.430
Definición Inglés:   A phosphoric diester hydrolase that removes 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated OLIGONUCLEOTIDES. It has low activity towards POLYNUCLEOTIDES and the presence of 3'-phosphate terminus on the substrate may inhibit hydrolysis. 
Nota Histórica Inglés:   2004; use PHOSPHODIESTERASE I (NM) 1980-2003 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   38147 
Identificador Único:   D043264 

Ocurrencia en la BVS: 		 

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